Motif ID: TAL1_TCF{3,4,12}.p2

Z-value: 0.791


Transcription factors associated with TAL1_TCF{3,4,12}.p2:

Gene SymbolEntrez IDGene Name
TAL1 6886 T-cell acute lymphocytic leukemia 1
TCF12 6938 transcription factor 12
TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
TCF4 6925 transcription factor 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TAL1chr1_-_47695442-0.629.7e-03Click!
TCF4chr18_-_53071225-0.582.0e-02Click!
TCF3chr19_-_16523270.233.9e-01Click!
TCF12chr15_+_57210972-0.194.8e-01Click!


Activity profile for motif TAL1_TCF{3,4,12}.p2.

activity profile for motif TAL1_TCF{3,4,12}.p2


Sorted Z-values histogram for motif TAL1_TCF{3,4,12}.p2

Sorted Z-values for motif TAL1_TCF{3,4,12}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TAL1_TCF{3,4,12}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_133494275 3.919 TF
transferrin
chr17_+_41003184 1.993 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr16_-_29910340 1.814 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr12_-_103311380 1.671 NM_000277
PAH
phenylalanine hydroxylase
chr14_-_94849552 1.350 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_-_158300517 1.295 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_-_150738232 1.271 CTSS
cathepsin S
chr22_+_24979717 1.120 NM_013430
GGT1
gamma-glutamyltransferase 1
chr1_-_160681552 1.069 NM_001778
CD48
CD48 molecule
chr6_-_41703938 0.972 NM_001167827
TFEB
transcription factor EB
chr16_+_2588000 0.937 PDPK1
3-phosphoinositide dependent protein kinase-1
chr16_+_2587989 0.928 PDPK1
3-phosphoinositide dependent protein kinase-1
chr8_-_80993009 0.889 NM_001025252
TPD52
tumor protein D52
chr4_+_69962191 0.844 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_-_73848766 0.777 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr1_-_150738255 0.723 CTSS
cathepsin S
chr16_+_12058963 0.710 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_-_142783975 0.685 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_-_73848530 0.650 NM_001244950
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_32716839 0.634 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr14_-_107179043 0.623 IGHA1
immunoglobulin heavy constant alpha 1
chr10_+_7745325 0.620 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_+_75315632 0.545 SEPT9
septin 9
chr10_+_81073763 0.544 ZMIZ1
zinc finger, MIZ-type containing 1
chr15_-_60919642 0.543 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr12_-_123187842 0.538 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr11_+_67222817 0.528 NM_145200
CABP4
calcium binding protein 4
chr10_+_7745229 0.528 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr13_+_113741668 0.527 MCF2L
MCF.2 cell line derived transforming sequence-like
chr20_+_46130600 0.525 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr6_-_11382501 0.504 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_-_150738292 0.493 NM_001199739
NM_004079
CTSS

cathepsin S

chr19_-_11688441 0.488 ACP5
acid phosphatase 5, tartrate resistant
chr1_+_50569581 0.474 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_96956458 0.455 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr10_+_7745284 0.454 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_+_94292737 0.453 PEG10
paternally expressed 10
chrX_-_2886285 0.449 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr1_+_207262211 0.407 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr10_+_7745341 0.399 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_17638064 0.398 FAM129C
family with sequence similarity 129, member C
chr7_+_94292816 0.396 PEG10
paternally expressed 10
chr11_-_128894008 0.393 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr19_+_18208596 0.389 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chrX_+_128913881 0.388 NM_018990
SASH3
SAM and SH3 domain containing 3
chr19_-_11688484 0.386 ACP5
acid phosphatase 5, tartrate resistant
chr9_+_35673852 0.384 NM_001216
CA9
carbonic anhydrase IX
chr22_-_43343046 0.383 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr1_+_26856259 0.377 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr7_+_26403944 0.365 NM_001199838
SNX10
sorting nexin 10
chr2_-_89513056 0.361 IGKC
immunoglobulin kappa constant
chr1_-_93342706 0.356 NM_001252271
FAM69A
family with sequence similarity 69, member A
chrX_-_33357725 0.350 NM_000109
DMD
dystrophin
chr6_-_32920812 0.346 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr9_-_130667571 0.341 LOC100131355
ST6GALNAC6
uncharacterized LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr18_+_29171729 0.341 NM_000371
TTR
transthyretin
chr14_-_94759556 0.336 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_+_39734475 0.334 NM_203354
CTAGE5
CTAGE family, member 5
chr22_+_40322609 0.331 GRAP2
GRB2-related adaptor protein 2
chr19_-_33360641 0.327 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr7_-_37025696 0.327 ELMO1
engulfment and cell motility 1
chr1_+_207262583 0.324 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta


chr1_-_92951593 0.318 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr22_+_36649172 0.317 APOL1
apolipoprotein L, 1
chr11_-_66675334 0.311 NM_022172
PC
pyruvate carboxylase
chr13_+_97874540 0.304 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr10_+_5238756 0.302 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr2_-_25466795 0.294 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_+_36772696 0.289 NM_024676
SH3D21
SH3 domain containing 21
chr10_-_75457553 0.288 NM_001144000
AGAP5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
chr10_-_14050453 0.276 FRMD4A
FERM domain containing 4A
chr2_-_183387063 0.264 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr3_-_11623829 0.258 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr19_-_11688508 0.254 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr2_-_166930130 0.250 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr2_+_68592317 0.249 NM_002664
PLEK
pleckstrin
chr22_+_22550112 0.247


chr15_+_58724174 0.246 NM_000236
LIPC
lipase, hepatic
chr17_+_37895023 0.242 NM_001242442
GRB7
growth factor receptor-bound protein 7
chr17_-_49124128 0.240 NM_001251971
SPAG9
sperm associated antigen 9
chr11_+_46694514 0.239 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr8_+_9413390 0.237 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr16_+_2588021 0.234 PDPK1
3-phosphoinositide dependent protein kinase-1
chrX_+_128913897 0.224 SASH3
SAM and SH3 domain containing 3
chr22_+_36649116 0.209 NM_001136540
NM_001136541
NM_003661
NM_145343
APOL1



apolipoprotein L, 1



chr3_+_63884074 0.207 NM_001177387
ATXN7
ataxin 7
chr7_-_155437056 0.202


chr17_-_56296965 0.198 NM_001165927
MKS1
Meckel syndrome, type 1
chr17_-_67311773 0.192 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr15_+_81489218 0.189 NM_001172128
IL16
interleukin 16
chr3_+_10068123 0.185 FANCD2
Fanconi anemia, complementation group D2
chr19_-_4338750 0.184 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr2_+_102615456 0.183 NM_173343
IL1R2
interleukin 1 receptor, type II
chr21_-_27423423 0.180


chr12_-_7261788 0.179 NM_016546
C1RL
complement component 1, r subcomponent-like
chr19_+_45417920 0.175 NM_001645
APOC1
apolipoprotein C-I
chr1_-_153919140 0.174 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr7_+_94539209 0.174 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr8_-_66701175 0.173 NM_002603
PDE7A
phosphodiesterase 7A
chr2_+_136288953 0.172 NM_015361
R3HDM1
R3H domain containing 1
chr5_-_131879172 0.172 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr15_+_25101697 0.169 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr3_-_178984789 0.165 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr1_+_244216506 0.161 NM_006352
ZNF238
zinc finger protein 238
chr15_+_74900712 0.160 NM_003992
CLK3
CDC-like kinase 3
chr12_-_48119224 0.157 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr11_+_113659924 0.157 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr10_+_63808968 0.156 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_50571963 0.152 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_+_2587951 0.151 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr5_+_139876504 0.148 ANKHD1
ankyrin repeat and KH domain containing 1
chr6_+_36210944 0.142 NM_173676
NM_001145716
PNPLA1

patatin-like phospholipase domain containing 1

chr1_-_9129666 0.141 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr6_-_163148798 0.139 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr5_+_167718485 0.136 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr6_+_64286348 0.133 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr16_+_89679715 0.132 NM_001128141
DPEP1
dipeptidase 1 (renal)
chr3_+_141043054 0.130 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chrX_+_78200828 0.130 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr12_-_108955164 0.127 NM_014706
SART3
squamous cell carcinoma antigen recognized by T cells 3
chrX_+_47082416 0.123 NM_001170460
CDK16
cyclin-dependent kinase 16
chr14_+_71996041 0.122 NM_015556
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr14_-_24423329 0.120 C14orf167
chromosome 14 open reading frame 167
chr1_+_226016428 0.116 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chrX_-_110513750 0.115 NM_014289
CAPN6
calpain 6
chr2_+_74057969 0.107 STAMBP
STAM binding protein
chr12_+_120105656 0.106 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr15_-_74494780 0.105 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr3_+_10068097 0.105 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chrX_-_32430370 0.105 NM_004011
NM_004012
DMD

dystrophin

chr16_+_68279297 0.104 PLA2G15
phospholipase A2, group XV
chr17_-_38073792 0.102 NM_018530
GSDMB
gasdermin B
chr1_-_51984994 0.101 NM_001981
EPS15
epidermal growth factor receptor pathway substrate 15
chr17_+_6659155 0.100 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr8_+_56015013 0.100 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr21_-_34185943 0.096 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr17_-_56406120 0.092 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr7_+_73245192 0.092 NM_001305
CLDN4
claudin 4
chr3_-_120068077 0.091 NM_001099678
LRRC58
leucine rich repeat containing 58
chr4_+_88571453 0.090 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chrX_-_154563735 0.090 NM_001289
CLIC2
chloride intracellular channel 2
chr3_-_114478117 0.089 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr12_+_62954275 0.086 MON2
MON2 homolog (S. cerevisiae)
chr1_-_9129620 0.085 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_128841432 0.085 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr3_-_187454247 0.085 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr19_-_39368889 0.085 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr2_-_25467078 0.083 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr16_-_71610948 0.082 NM_000353
TAT
tyrosine aminotransferase
chr6_-_22297729 0.080 NM_000948
PRL
prolactin
chr1_+_24840800 0.077 NM_001251980
NM_001251982
NM_001251985
RCAN3


RCAN family member 3


chr8_-_20040612 0.077 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr1_-_153013593 0.074 NM_006945
SPRR2D
small proline-rich protein 2D
chr12_-_131002409 0.071 NM_015347
RIMBP2
RIMS binding protein 2
chr12_-_7848324 0.071 NM_020634
GDF3
growth differentiation factor 3
chr13_-_27334777 0.069 NM_005288
GPR12
G protein-coupled receptor 12
chr6_+_126240369 0.068 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr8_+_136470108 0.068 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr19_+_46195740 0.067 NM_001163377
NM_017659
QPCTL

glutaminyl-peptide cyclotransferase-like

chr14_-_69260630 0.066 NM_001244698
NM_004926
ZFP36L1

zinc finger protein 36, C3H type-like 1

chr5_-_169724817 0.066 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_150954498 0.064 NM_003568
ANXA9
annexin A9
chr16_+_68279206 0.062 NM_012320
PLA2G15
phospholipase A2, group XV
chr16_-_29874348 0.061 NM_006319
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr8_+_9413439 0.061 NM_003747
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_-_86850959 0.061 NM_001198951
NM_001198952
NM_005667
RNF103


ring finger protein 103


chr6_+_29364331 0.060 NM_013936
OR12D2
olfactory receptor, family 12, subfamily D, member 2
chr6_+_31514627 0.060 NM_001144962
NM_001144963
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr17_+_55055467 0.059 NM_021626
SCPEP1
serine carboxypeptidase 1
chr12_-_108954952 0.059 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr6_+_167536240 0.057 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr6_-_30128688 0.055 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr8_+_21911062 0.054 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr18_+_43405544 0.054 NM_213602
SIGLEC15
sialic acid binding Ig-like lectin 15
chr17_-_16875388 0.052 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr16_+_77224827 0.051 NM_014940
MON1B
MON1 homolog B (yeast)
chr3_+_49044494 0.050 NM_018031
WDR6
WD repeat domain 6
chr8_-_38239466 0.050 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr3_-_149095517 0.050 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr5_+_161275897 0.046 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_+_163149001 0.043 NM_001080379
PACRG
PARK2 co-regulated
chr6_-_32160289 0.043 GPSM3
G-protein signaling modulator 3
chr1_+_204042191 0.042 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr1_+_209878135 0.042 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr19_-_4103200 0.041 MAP2K2
mitogen-activated protein kinase kinase 2
chr1_+_100326765 0.040 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr22_-_36556781 0.040 NM_145640
APOL3
apolipoprotein L, 3
chr17_-_1090562 0.034 NM_001159746
ABR
active BCR-related gene
chr8_+_74903563 0.033 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr17_-_72542244 0.032 NM_006678
CD300C
CD300c molecule
chrX_+_153770458 0.031 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_+_11863520 0.030 USP47
ubiquitin specific peptidase 47
chr19_+_10812111 0.029 NM_031209
QTRT1
queuine tRNA-ribosyltransferase 1
chr12_-_50236868 0.029 NM_181708
BCDIN3D
BCDIN3 domain containing
chr6_-_163148800 0.029 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr19_-_17516383 0.028 NM_004335
BST2
bone marrow stromal cell antigen 2
chr7_+_141478241 0.028 NM_016944
TAS2R4
taste receptor, type 2, member 4
chr19_+_17516502 0.028 LOC100507535
uncharacterized LOC100507535
chr13_+_49794471 0.027 NM_001507
MLNR
motilin receptor
chr17_-_56606534 0.026 SEPT4
septin 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.